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Julian Bowen Consort Dining Table, Honey, Height: 77, Width: 92, Depth: 92cm

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To develop harmonized, evidence- and consensus-based standards for reporting outcomes in clinical trial reports through integration with the Consolidated Standards of Reporting Trials (CONSORT) 2010 statement. Authors should provide a balanced discussion of the strengths and limitations of the trial and its results. Authors should consider issues related to risks of bias, precision of effect estimates, the use of multiple outcomes and analyses, and whether the intervention was delivered and taken up as planned. Discussion: generalisability Item 21: generalisability (external validity, applicability) of the trial findings Calvert M, Blazeby J, Altman DG, et al. Reporting of patient-reported outcomes in randomized trials: the CONSORT PRO extension. JAMA. 2013;309(8):814–22. When cleaning the furniture please use the correct cleaning products! Avoid using everyday household products as these can leave behind a layer of oil that will build up over time. This causes furniture (especially solid oak) to lose its colour and can strip the furniture down. Since the revision in 2001, the evidence base to inform CONSORT has grown considerably; empirical data highlighting new concerns regarding the reporting of randomized trials. Therefore, a third CONSORT Group meeting was held in 2007, resulting in publication of a newly revised CONSORT Statement [1] and explanatory document [2] in 2010. Users of the guideline are strongly recommended to refer to the most up-to-date version while writing or interpreting reports of clinical trials.

CONSORT 2010 Statement: updated guidelines for reporting

The interventions for each group with sufficient details to allow replication, including how and when they were actually administeredCreate a traditional farmhouse look in your home with the Consort Table. Constructed from solid Malaysian Hardwood in a honey pine lacquer finish allows this table to match almost anything, or simply match with the Consort dining chairs! This space-saving table folds into a half-moon shape, practical for those with a small kitchen. Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:a1655. Authors should indicate the intended sample size for the trial and how it was determined, including whether the sample size was determined a priori using a sample size calculation or due to practical constraints. If an a priori sample size calculation was conducted, authors should report the effect estimate used for the sample size calculation and why it was chosen (e.g. the smallest effect size of interest, from a meta-analysis of previous trials). If an a priori sample size calculation was not performed, authors should not present a post hoc calculation, but rather the genuine reason for the sample size (e.g. limitations in time or funding) and the actual power to detect an effect for each result (Item 17). Item 7b: when applicable, an explanation of any interim analyses and stopping guidelines Little J, Higgins JPT, Ioannidis JPA, Moher D, Gagnon F, Von Elm E, et al. STrengthening the REporting of Genetic Association studies (STREGA)-an extension of the STROBE Statement. J Clin Epidemiol 2009;62:597e608 Within person randomised trials present some particular challenges. One problem is the potential for a “carry across effect,” whereby, for example, an intervention applied to one eye or in an area of the mouth can affects the other eye, systemically, 14 or other areas of the mouth, locally. 15 16 Success or failure of the first replacement hip in a patient requiring bilateral hip replacement can affect the success or failure of the second hip operation. 17 A related problem is the possibility of participants dropping out of the trial if the two interventions are not applied concurrently.

The CONSORT statement - PMC - National Center for The CONSORT statement - PMC - National Center for

Simmons JP, Nelson LD, Simonsohn U. False-positive psychology: undisclosed flexibility in data collection and analysis allows presenting anything as significant. Psychol Sci. 2011;22(11):1359–66.

CONSORT Non-pharmacological treatment interventions: Boutron I, Altman DG, Moher D, Schulz KF, Ravaud P; CONSORT NPT Group. CONSORT Statement for Randomized Trials of Nonpharmacologic Treatments: A 2017 Update and a CONSORT Extension for Nonpharmacologic Trial Abstracts. Ann Intern Med. 2017;167(1):40-47. PMID: 28630973 Multiple statistical analyses can lead to false-positive results, especially when using stopping guidelines based on statistical significance. Any interim analyses should be described, including which analyses were conducted (i.e. the outcomes and methods of analysis), when they were conducted, and why (particularly whether they were pre-specified [ 78]). Authors should also describe the reasons for stopping the trial, including any procedures used to determine whether the trial would be stopped early (e.g. regular meetings of a data safety monitoring board) [ 79]. Methods: randomisation—sequence generation Item 8a: method used to generate the random allocation sequence Simes R. Publication bias: the case for an international registry of clinical trials. J Clin Oncol. 1986;4(10):1529–41. STRICTA Controlled trials of acupuncture: MacPherson H, Altman DG, Hammerschlag R, Youping L, Taixiang W, White A, Moher D; STRICTA Revision Group. Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement. PLoS Med. 2010;7(6):e1000261. PMID: 20543992

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