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Patients were further stratified into lower (< 300 cells/μL) and higher (≥300 cells/μL) blood eosinophil groups. The impact of the blood eosinophil levels on the future rate of exacerbations was evaluated in patients with higher or lower eosinophil levels. Medpace’s TrialPACE system allows for the safe and secure collection of PRO and eCOA data directly from patients through multiple platforms. This easy-to-use, yet sophisticated tool can increase active subject participation in the research. A diary is a place you can feel safe expressing yourself without judgment. You can write honestly and candidly about any topic you decide, without worrying if someone else will see it. It is a place where your hopes and dreams can flow freely. How much does a Penzu diary cost?

Wearable Device Integration:Allows native device integrations with smart watches, glucometers, scales, thermometers, and other smart devices. Although not many ePRO vendors openly advertise about having this feature to create a training guide, if you’ve found the perfect ePRO solution for your trial and would require a training manual to be created for your patient population, it is advisable to directly approach the vendor to request a custom training and see if this will be within the realm of what the vendor will be willing to offer you for your particular study. 10. Consultation With ePRO Experts It is advised to determine the deal-breaker features that you would like to have as part of the ePRO experience for patients, so you can consult the vendors and see how they are able to help you with them. For example, you may require custom graphs and survey notifications, or your trial participants may require a device to be provided to complete their e-diary entries. To make it easier for you to understand which features you may like to see in your ePRO solution, we’ve put together a list of some of the most widely offered features by ePRO/eCOA vendors. 13 Key Features To Look For In ePRO 1. Bring Your Own Device (BYOD)

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Integration With Other Clinical Trial Management Systems: Offers the ability to integrate ePRO with your EDC, IRT or other systems as needed. Technical support to complete a needed integration is available from Curebase’s technical team.

Schumann DM, Tamm M, Kostikas K, Stolz D. Stability of the blood Eosinophilic phenotype in stable and exacerbated COPD. Chest. 2019;156:456–65.Flexible Device Support: Medrio ePRO offers high flexibility in device support; patients are able to use their own devices to respond to survey questions in real-time and remotely, regardless of where they are located. Ennov Clinical Suite: Ennov offers a clinical trials management software ecosystem which includes Ennov ePRO, along with Ennov EDC, Ennov RTSM, Ennov CTMS, Ennov eTMF, TMF Archive, eLearning. Kostikas K, Aalamian-Mattheis M, Pagano VA, Nunez X, Fogel R, Patalano F, Clemens A. Early changes in eDiary COPD symptoms predict clinically relevant treatment response at 12 weeks: analysis from the CRYSTAL study. COPD. 2018;15:185–91.

More than 15 million people have tried it, and more than 300.000 people have already rated it with the highestIn clinical trials, another common term that is associated with ePRO is eCOA, which stands for “electronic clinical outcome assessments”. This term refers to all electronically recorded outcomes, inclusive of patient-reported outcomes. While eCOA is the broader category which contains ePRO, many clinicians will use this term instead to refer to electronic patient-reported outcomes. Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD). Available at: www.goldcopd.org. Accessed on 6 Dec 2019. There are numerous benefits to using ePRO in clinical trials for both patients and clinicians, and this single switch to a paperless data collection process has potential to significantly improve the overall patient study experience.

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